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The membrane-bound folate receptor has the highest affinity for folate (Kd ∼0.1–1 nmol/l), characteristically binds folic acid, reduced folates, many antifolate drugs, and folate conjugates, and transports them by a non-classical endocytic mechanism 881,885

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Improvement of levodopa induced dyskinesias by thalamic deep brain stimulation is related to slight variation in electrode placement: possible involvement of the centre median and parafascicularis complex