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The conversion of NAD+ to nicotinamide activates sirtuins (e.g., sirtuin-1) and poly[ADP-ribose] polymerases (PARPs), which promote mitochondrial biogenesis, energy expenditure, and antioxidant defenses [50,53] and DNA repair [54], respectively

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doi: 10.1016/j.redox.2023.102689 29 KumarA.KalitaJ.SinhaR

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