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10.1177/2050640619862721 United Eur Gastroenterol J

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Overall, the heterogeneity analysis (see supplementary material) indicated the study design and patient characteristics across the 12 included trials [19, 30, 35–37, 39, 41–43, 47, 48, 51] were sufficiently aligned with the PIONEER 8 trial and generalisable to the population of interest to be combined in the analyses