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Primary hyperoxalurias (PH) are caused by mutations in the genes encoding key enzymes of hepatic oxalate biosynthesis with many of these patients presenting with end-stage renal disease (ESRD) already at time of diagnosis [59, 60, 61, 62]

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Its between-group confidence interval spans zero and is wider than the point estimate, and the power for the observed difference is roughly 16%, so the trial was too small to detect the difference it observed — uninformative rather than null