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In rodent models, BPC-157 has been studied in the context of traumatic brain injury, peripheral nerve transection, and spinal cord injury, with findings including reduced lesion size, improved functional recovery scores, and enhanced nerve regeneration (Tudor et al., 2010

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Lin et al., 2026), and has been shown to rescue hyperexcitability in hippocampal neurons and reduce seizure-related electrocorticography (ECoG) activity patterns in DS mice (Lin et al., 2026)