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To disregard the negative effect of ion pair regents, 10 mM ammonium formate was added to 0.1% formic acid in water (solvent A) and 0.1% formic acid in methanol (solvent B) individually as the buffering agent

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T., et al., “Modulating Lipid Nanoparticles With Histidinamide‐Conjugated Cholesterol for Improved Intracellular Delivery of mRNA,” Advanced Healthcare Materials 13, no