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CB-839 inhibits glutaminase and decreases the viability of HCT-116 cells The SRB assay was used to determine the effect of the glutaminase inhibitor CB-839 on cell viability at doses ranging from 0.1 to 10,000 nM, targeting glutathione inhibition, applied for 48 h in HCT-116 CRC cells

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The potential health-promoting properties of coffee are largely attributed to its high content of bioactive compounds, particularly chlorogenic acids, which exhibit potent antioxidant and anti-inflammatory effects [80]