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g ., fish) generally live within an optimum range of temperatures, they have sufficient energy and oxygen supply and strong activities of detoxification enzymes and antioxidant enzymes (Pörtner, 2010), resulting in a high clearance rate of exogenous toxins and low sensitivity to their toxicity (Sokolova and Pörtner, 2007), the tolerance of the organism is reduced, and such a thermal stress at temperature extremes may further enhance the toxicity of a chemical (Jusup et al., 2016)

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10.1038/s41586-022-05342-4