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Disulfiram metabolites, including diethyldithiocarbamate (DDC), carbon disulfide (CS2), S-methyl N,N-diethylthiocarbamate sulfoxide (DETC-sulfoxide), S-methyl N,N-diethylthiocarbamate sulfone (DETC-sulfone), diethylthiomethylcarbamate, S-methyl-DDC, methyl diethylthiocarbamate sulfoxide, and methyl diethylthiocarbamate sulfone, play a crucial role in its pharmacological effects ( Studies have investigated the antibacterial activity of disulfiram and its metabolites, with results indicating that most DSF metabolites do not possess significant antibacterial activity, except for DDTC in Bacillus anthracis

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10.1002/ajh.25103 3 BigotK.GondouinP.BenardR.MontagneP.YoualeJ.PiazzaM.et al (2020)