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FDA labeling for both cyanocobalamin injection and Nascobal warns that "hypokalemia and sudden death may occur in severe megaloblastic anemia that is treated intensely with vitamin B12." As new red blood cells are made rapidly, potassium moves out of the blood

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Le Gal K, Ibrahim MX, Wiel Cl, Sayin VI, Akula MK, Karlsson C, Dalin MG, Akyürek LM, Lindahl P, Nilsson J, Bergo MO