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Immobilized glucose oxidase on hierarchically porous COFs and integrated nanozymes: a cascade reaction strategy for ratiometric fluorescence sensors | Analytical and Bioanalytical Chemistry | Springer Nature Link

There are 20%–30% of advanced HCC patients carrying gain-of-function mutations in β-catenin, which is the third most frequent mutation following the hTERT promoter and TP53

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As premises go, it is a reasonable one, and the enzyme has been reviewed as a genuine target in obesity and type 2 diabetes (the review of the roles of nicotinamide N-methyltransferase in obesity and type 2 diabetes published in BioMed Research International)