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In addition, injury LSECs can secrete many proinflammatory cytokines (e.g., IL-6 and TNF-α) and chemokines (e.g., CCL2 and CXCL9) to mediate liver inflammation [102]

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Others have taken an approach looking at single gene targets that are modified (either increased or decreased) in COPD patients (Bracke et al., 2006