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In addition, while the homogenous nature of the prescribed dietary intake deficit, physical activity goal and counseling frequency provided consistency, it may not fully reflect the need for approaches tailored to the health profiles of individuals or to different populations in clinical practice

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The AREDS formulation, consisting of vitamin C, vitamin E, beta-carotene, copper, and zinc, was shown to reduce the risk of AMD progression by 34% over a median of 6.3 years in participants with a high risk of disease progression (i.e., heavy smokers and ethnicity) [91,92]