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Of note, even though the template library of manually labeled hippocampal volumes consisted of data from healthy young adults, using the ANIMAL pipeline combined with this template library results in a method fairly resistant to developmental volumetric deviations, as shown by its high Dice Kappa and Jaccard similarity values (Collins and Pruessner, 2010)

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(2021) Harnessing tumor necrosis factor alpha to achieve effective cancer immunotherapy