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Oral administration of LSN3353871 to mice expressing human Lp(a) resulted in dose-dependent increases in the circulating levels of LSN3353871 and dose-dependent decreases of up to 78% in the levels of Lp(a), with a median effective dose (ED 50 ) of 14 mg kg −1 twice daily (BID) within five days of dosing

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In pursuit of harmony, on behalf of European federation for clinical chemistry and laboratory medicine (EFLM) working group for preanalytical phase (WG-PRE)