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By binding to cardiolipin, Elamipretide stabilizes mitochondrial cristae, improves membrane integrity, and enhances oxidative phosphorylation (Minkler et al., 2015)

Feature_2024-11-11

Size:100 MG

In the desensitized state, the LBD-TM linker strain due to bound agonist is relaxed via rearrangements of LBD from a dimer of dimer scheme to a pseudo-4 fold symmetric arrangement, where the LBD dimers are disrupted (Fig