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Whether prolonged, systemic treatments with reductive agents that cross the blood brain barrier would prove to be an effective preventive treatment for patients at high risk remains to be established

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Stable isotope experiments can be used to discern the source of methylglyoxal, as conversion of [U- 13 C 2 ]glycine to methylglyoxal results in methylglyoxal with one labeled carbon (m + 1) (Fig

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