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It is not known whether the GTPase activity of CobW provides an additional ‘check-point’ for metal fidelity, or whether the chelatase CobNST, whose in vitro insertase activity appears remarkably specific for Co(II) [155], is solely responsible for metal selectivity at the insertion step

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(2) Kopchick JJ, Berryman DE, Puri V, Lee KY, Jorgensen JOL

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