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Recently, it has been demonstrated that inhibitors of the PI3K/AKT pathway caused an acute increase in glucose blood levels and insulin serum levels in wild-type mice and mice with tumor allografts

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For the Ers parameter, we observed an improvement of nearly 70% for ToAP3-treated mice and almost 50% for ToAP4-treated mice 30 days after the BLM instillation (Figure 4B)