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So, to protect the hydrolysis of the drug, A group used PLGA-β-CD to encapsulate methotrexate (MTX), an antifolate that competitively inhibits dihydro folate receptor (DHFR) which is necessary to synthesize purines and pyrimidines thereby stopping DNA/RNA synthesis in cancer cells leading to its death

Esta fórmula incluye una administración liposomal con un complejo de fosfolípidos