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They first elucidated that ISL relieved liver fibrosis by inducing HSCs ferroptosis through repressing GPX4 expression and increasing the expression of transferrin receptor (TFR) and divalent metal transporter 1 (DMT1), thus producing a large number of ROS (Huang et al., 2022)

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Your body uses a form of vitamin B3 called nicotinamide to build NAD+ , the energy currency that powers mitochondria and many cell-repair processes