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On the above basis, sulforaphane has been shown to downregulate NF-κB activity in the following cell types under a variety of inflammatory conditions: bone marrow-derived dendritic cells [74]

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Another pathway of interest is the mitogen activated protein kinase (MAPK) cascade, which can be activated by H 2 O 2 and subsequently translocated into the nucleus to activate specific transcription factors (Lebrun-Garcia et al