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Moreover, mice with heart-specific overexpression of ABCB8, which exports iron out of the mitochondria, were more resistant to DOX cardiotoxicity, although the role of ABCB8 in ferroptosis has not been directly investigated 58

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Further, inhibition of TRPM7 activity attenuates RA articular cartilage destruction and chondrocyte ferroptosis by suppressing the PKCα-NOX4 axis (129)