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J Clin Exp Cardiolog 3: 201

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It has also been observed that the host antiviral defense response in the early stages of SARS-CoV-2 infection involves heightened expression of azurophilic granule proteins proteinase 3, MPO, elastase, and cathepsin G, leading to potential tissue damage stimulated by the release of antiviral enzymes through neutrophil degranulation as part of the mechanism of viral clearance (233)