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About the SBIR/STTR Programs | National Institute on Drug Abuse (NIDA)

The activities of ER folding enzymes are highly dependent on the reduction/oxidation (redox) environment, and even small perturbations in the redox status greatly affect enzymatic activity and, as a result, protein folding kinetics [74]

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An additional 1 WT-sham, 2 KO-VSG and 2 WT-VSG mice died (or were found moribund) during the period of metabolic phenotyping that occurred between weeks 8 and 15