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Furthermore, the immunohistochemistry analysis evaluated the protective effects of the Au-PX-PLGA on dopaminergic neurons in the striatum and tyrosine hydroxylase, which is an essential enzyme in dopamine synthesis, served as the biomarker for dopaminergic neuron integrity

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Silencing of SlBEL11 alters the expression of enzyme genes in the carotenoid biosynthetic pathway To explain how SlBEL11 regulated carotenoid synthesis at the genetic level, we examined the transcript levels of main enzyme genes from carotenoid biosynthesis pathway ( PSY1 , PSY2 , PDS , ZDS , CRTISO , LCY-b1/b2 , CYC-b , and LCY-e) by qRT-PCR (Figure 2)