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GI side effects affect 10% to 40% of GLP-1 users, particularly during the first few weeks and during each dose escalation

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Figure 9 4 Discussion Glutamine, an amino acid needed for protein synthesis and for cellular proliferation, is converted to glutamate by glutaminase, and the disruption of cancer metabolism through glutamine inhibition has been an attractive target for solid and hematological tumor therapies for many years

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