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In a recent 12-week, randomized, placebo-controlled trial in untreated hypertensive subjects, daily intake of aged garlic extract (1.2 g of which contained 1.2 mg of S-allyl-L-cysteine [SAC]) was shown to significantly lower SBP by 11 mm Hg and DBP by 6 mm Hg on average in 50%-60% of participants, but reductions in blood pressure were not reported in 40%-50% of participants compared to placebo (110)

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Gvozdjáková et al [99] reported that daily intake of CoQ10 (30 mg), L-carnitine (440 mg), vitamin C (12 mg), and vitamin E (75 IU) improved sperm concentration and pregnancy rates in infertile individuals