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Moreover, chitosan-decorated SeNPs (CTS-SeNPs) are used to treat T2D by prolonging the in vivo half-life of the therapeutic peptide BAY 55-9837 and slowing its renal clearance rate, proving that BAY 55-9837-loaded CTS-SeNPs possess a desirable sustained-release profile and high stability that could enhance the half-life of low-molecular-weight therapeutics by increasing their apparent molecular size [445]