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However, this histamine does not enter our bloodstream as it is broken down by an enzyme called Diamine Oxidase (DAO)

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And, in a meta analysis looking at the use of berberine in women with polycystic ovarian syndrome (PCOS), it was found that berberine may: Reduce visceral fat mass Improve ovulation rate Alter fat distribution However, in the majority of these studies, dietary and lifestyle changes were implemented alongside berberine use