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It has been proposed that the nourishing effects of MSM on skin, hair, and fingernails are due to its high sulfur content ( 35 S] MSM was detected in the blood, spleen, and hair tissues, and the administered MSM might have been metabolized to yield certain sulfur-containing compounds, such as keratin, a key component of hair and nail in rats ( The gut is host to a diverse and abundant community of bacteria that influence health and disease susceptibility