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To prevent an unfavourable cellular oxidation state and glycolytic stalling, KRAS* also promotes the rapid reduction of glycolysis-derived pyruvate to lactate 23,39,40 (FIG

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10.1016/j.ceb.2009.08.005 [DOI] [PMC free article] [PubMed] [Google Scholar] 40.Morrison BJ, Labo N, Miley WJ, Whitby D

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