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Abbreviations: ATF4 activating transcription factor 4 NRF2 nuclear factor, erythroid 2 like 2 PDAC pancreatic ductal adenocarcinoma ROS reactive oxygen species CoA coenzyme A ACSL acyl-CoA synthetase long chain family member GSH (reduced) glutathione Fe/S iron/sulfur CSA cysteine sulfinic acid NADPH (reduced) nicotinamide adenine dinucleotide phosphate Footnotes Conflicts of interest: S.J.D

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Antibacterial testing against Escherichia coli and Streptococcus iniae revealed that GO nanosheets were more effective against Gram-positive bacteria