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Tom Frieden, the former CDC director, granted as much to STAT News: the Make America Healthy Again movement is right that chronic disease and corporate influence are real problems

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Unlike the relatively stable hormonal environment in men, women experience cyclical variations in 17β-estradiol (E2) and progesterone (P4) that directly influence key metabolic processes, including glucose homeostasis, lipid oxidation, amino acid turnover, and mitochondrial bioenergetics [3,4,5]