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The TGF-β/Smads pathway negatively regulates the paired-box homeotic gene 3 (PAX3), which works synergistically with the SRY-Box Transcription Factor 10 (SOX10) to upregulate MITF, dependent on a cAMP-response element (CRE) 46 , 47

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Williams’s three guardianship attorneys, the only lawyers recognized by the court — who are supposed to represent Williams’s interests as they see them — are not authorized to speak to the media