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(2) the mechanisms underlying the therapeutic effects of VNS need to be elucidated further to guide the development of personalized treatment strategies, and (3) most studies, so far, have relatively small sample sizes and variations in stimulation parameters and protocols, making it challenging to draw definitive conclusions

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HA Injections Used as an alternative non-operative treatment option for knee osteoarthritis Provides temporary joint lubrication and symptom relief, but did not demonstrate the same level of benefits as PRP injections based on the comparative analysis Often more cost-effective and covered by insurance Cost Comparison In general, PRP injections tend to be more expensive than HA injections, as insurance does not pay for these injections