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The latter differentiate into differentiating spermatogonia (type A1-A4, intermediate spermatogonia, type B), thereby entering meiosis after undergoing rapid mitotic division ( s , A pr , and A al ), whose key function is to maintain an undifferentiated state by directly repressing the expression of Kit , a hallmark of spermatogonial differentiation, is crucial for the self-renewal of SSCs ( dark and A pale , based on nuclear morphology

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Type 2 diabetes and oxidative stress and inflammation: Pathophysiological mechanisms and possible therapeutic options