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Safety issues and harmful pharmacological interactions of nutritional supplements in Duchenne muscular dystrophy: considerations for Standard of Care and emerging virus outbreaks - PMC

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The resemblance of telomeres with DNA breaks requires the suppression of several DNA damage response (DDR) pathways that otherwise target double-strand (ds) DNA breaks and ssDNA, which make telomeres particularly susceptible to erroneous activation of the DDR and cell cycle arrest 4