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Nrf2/Keap1/ARE regulation by plant secondary metabolites: a new horizon in brain tumor management | Cell Communication and Signaling | Springer Nature Link

Signal peptides are necessary and sufficient for protein translocation across membranes if the fused polypeptide substrate can be maintained in an export competent state, a function that can be achieved by one of two separate pathways (142, 808)

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They feed, grow, and fatten in fresh water