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HMP Pathway Simplified: NADPH Role & G6PD Deficiency Explained

In addition, daidzein is converted to formononetin catalyzed by CYP1A2 (cytochrome P450 family 1 subfamily A polypeptide 2: Gene ID 1543) enzyme and may also produce dihydrodaidzein, equol, and others (Atherton et al., 2006)

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ATM deficiency caused sensitization and early differentiation of melanoblasts leading to depletion from the stem cell niche which caused depigmentation of the follicle in subsequent hair cycles