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Indole-3-acetamide from gut microbiota activated hepatic AhR and mediated the remission effect of Lactiplantibacillus plantarum P101 on alcoholic liver injury in mice

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Among the proposed mechanisms affecting oligodendrocytes functions, we can list the formation of protein aggregates, inducing ER stress, and the robust pro-inflammatory environment characterized by a high level of interferon γ (IFN-γ) [20], and dysregulation of myelination and lipid signaling pathways [51]