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Some people become B12 deficient due to other reasons such as a medical condition or alcohol misuse

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Increased intestinal permeability — often referred to as “leaky gut” — has been linked to a range of conditions, including: Inflammatory Bowel Disease (IBD) Celiac Disease Irritable Bowel Syndrome (IBS) Metabolic Disorders Systemic Inflammation Conversely, reduced permeability can impair nutrient uptake