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Increased dopamine output from the adrenal glands attenuated the increase in serum TNF- α levels in a mouse model of endotoxemia (Shimojo et al., 2019), and in diabetic, septic mice, treatment with the D1-like agonist fenoldopam attenuated inflammation by inhibiting p65 NF-kB phosphorylation in splenocytes (Feketeova et al., 2018)

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