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Lipid-based nanocarriers (such as nanostructured lipid carriers and liposomes) and polymeric nanoparticles can protect CGA from degradation and provide controlled intestinal release

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252 The NICD then translocates into the nucleus, where it forms a transcriptional complex with RBP-Jκ and Mastermind-like (MAML) coactivators, activating downstream targets such as Hes, Hey, c-Myc, and Bcl-2