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Nonetheless, the rate of apoptotic events after irradiation can be proportional to the number of fractions given, in line with the reassortment principle (cells cycling inter-fraction into states predisposed for interphase apoptosis) (Verheij and Bartelink, 2000)

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For example in this case arginine residue is strong basic positively charged amino acid and has ability to form multiple hydrogen bonds and salt bridge in comparison to cysteine