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The sequence in sv6D (QXXP, see Table 1) is unfavorable, whereas svC1 contains a favorable sequence (QXXQ), but both were poor substrates in vitro with freshly prepared enzyme solutions

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Parenteral administration is recommended for patients who are unable to take oral medications, such as before or after surgery, suffering from prolonged illness, or due to the inability to absorb vitamins in the gastrointestinal system