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Another class of gastric acid inhibitors known as histamine 2 (H 2 )-receptor antagonists (e.g., cimetidine, famotidine, and ranitidine), often used to treat peptic ulcer disease, has also been found to decrease the absorption of vitamin B 12 from food

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This study also examined changes in the basal level immunoreactivity of phospho-AKT, the apoptotic-stress response protein, in the GCL and INL of ND rats