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Conversely, Hb oxygenation is associated with a reduction in glycolytic flux, favoring the pentose phosphate pathway and subsequent NADPH production, which serves as a cofactor for various antioxidant systems [56]

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These include autoimmune diseases and those pertaining to metabolic syndrome in which immune derangement, faulty glucose handling, and dyslipidemia are responsible for interfering with fetal growth

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